Variant triage for geneticists, students and researchers — every variant ranked by clinical significance, with ClinVar lookups, pharmacogenomics and exportable reports. No per-variant lookups. No paywall. Research use only.
Upload your VCF file and get a clear, structured overview of genetic variants with priority indicators and human-readable explanations.
Most variant tools give you one lookup at a time for free — analysing the whole file is the paid part.
VariantTriage runs the entire VCF in your browser: every variant ranked, ClinVar and CPIC pharmacogenomics included, PDF and CSV export.
Free while we grow, with no card and no per-variant limits. Research use only.
| Gene | Position | Type | Priority | Note |
|---|---|---|---|---|
| RPGR | chrX:38,152,229 | Missense | High | Known pathogenic variant |
| RHO | chr3:14,182,883 | Missense | High | Likely pathogenic |
| USH2A | chr1:216,595,579 | Splice site | Medium | Variant of interest, VUS |
| PRPF31 | chr19:17,942,600 | Synonymous | Low | Likely benign |
| TULP1 | chr6:35,517,208 | Intronic | Low | Benign, no known effect |
— Features
Load any standard VCF file — GATK, DeepVariant, Illumina, 23andMe — and get structured results in seconds.
Variants are automatically triaged into High, Medium, and Low tiers. You always know where to look first.
No cryptic annotations. Each variant ships with a plain explanation and direct links to ClinVar and OMIM.
Your VCF is parsed in your browser and is never uploaded to our servers. Optional AI summaries send only variant-level data — no patient identifiers.
Export clean PDF reports or CSV tables. Share with colleagues or keep as structured documentation.
— Workflow
Four steps. Under sixty seconds. No configuration required.
— Pharmacogenomics
VariantTriage screens your VCF against 10 core pharmacogenes and maps diplotypes to metabolizer phenotypes, then surfaces CPIC-level A/B drug guidance — from clopidogrel and warfarin to codeine, azathioprine and abacavir. Actionable drug–gene alerts are flagged automatically. Research use only.
CYP2D6, CYP2C19, CYP2C9, VKORC1, SLCO1B1, DPYD, TPMT, UGT1A1, CYP3A5 and HLA-B.
Star-allele calling and activity-score phenotypes, translated into plain metabolizer status.
CPIC level A/B dosing guidance with contraindications flagged for the current sample.
The PGx profile is included in the exportable clinical report alongside variant triage.
— Comparison
See how we compare to typical alternatives for variant review workflows.
| Feature | VariantTriage | IGV / Generic viewers | Cloud-based tools |
|---|---|---|---|
| Instant priority triage | ✓ | ✗ | Partial |
| VCF parsed in-browser (not uploaded) | ✓ | ✓ | ✗ |
| Human-readable explanations | ✓ | ✗ | Partial |
| No setup / no CLI required | ✓ | ✗ | ✓ |
| PDF & CSV export | ✓ | Partial | ✓ |
| Free tier to start (no card) | ✓ | ✓ | ✗ |
| Works in any browser | ✓ | ✓ | ✗ |
— Why VariantTriage
Open your browser and start analyzing. No installation, no configuration, no command line required.
Your VCF is parsed locally and never uploaded to our servers. AI summaries send only variant-level data, without patient identifiers.
ClinVar and gnomAD lookups send only the identifiers needed. We treat genomic data as a GDPR special category (Art. 9).
From raw VCF to prioritized, readable output in under 60 seconds. No queue, no wait, no friction.
— Pricing
Start free. Upgrade when you're ready.
Perfect for learning variant interpretation. Start with real genomics datasets, no credit card required, forever free.
Full access for individual researchers, clinicians and analysts.
For clinical labs, research groups and small teams.
— FAQ
Everything you need to know about VariantTriage.
— Get started today
Work through variant data faster and with more clarity — straight in your browser, nothing to install. Research use only.